I ll give you my personal opinion, always relative when we are talking about flavours and attys.
You said that you have a 510 titan-tank, and so have I. have you tried the Titan Tobacco e-liquid? It's the one that comes with the TW titan-tank kit. I find it wonderful.
Another great eliquid I found here is the Patriot Range Tobacco Americano, similar to Titan Tobacco but with a fresh hint at the end.
I would suggest then to use the titan-tank with its tanks instead the CE2 clearomizers, It is as told a personal opinion, someone here love them i personally hate them.
I tried a couple of them and I find they change the taste of flavours, they give a subtle flavour by themselves and also the drag feel is different. I might be wrong but the third of them went directly into the bin with all the eliquid inside
Then if you are an heavy user you will find that going on a system like Tornado Ego or still better Ego-c will be cheaper to maintain and more satisfactory.