University of East London The electronic-cigarette: Effects on desire to smoke.

[Astrecks]

Below is a study recently completed by the University of East London on The electronic-cigarette: Effects on desire to smoke, withdrawal symptoms and cognition, to download press the link

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[real-player]

wow , nicotine was associated with superior working memory performance.  Recall  was consistently higher in the nicotine group with significant differences  real good read thanks jeff for sharing this with us

[FredSpencer]

wow , nicotine was associated with superior working memory performance.  Recall  was consistently higher in the nicotine group with significant differences  real good read thanks jeff for sharing this with us

I'm gonna increase my nic strength ..... I need all the help I can get.

[vp_smoker]

Thanks for the share Jeff, interesting read.

[real-player]

trust u fred lol

[efrenchy]

Very interesting!!!
Thanks

[Kenneth131]

Thanks Jeff you know how much i like my studies and stats so this is great reading

[Astrecks]

 

[Housey66]

Hello
I am new to all this vaping as only started 9 days ago, however not wanted or thought about a real cigarette since and that is saying something for me.  Saving money, smell nicer and no cough in the morning.  Thanks TW.  My brother discovered you in december last year and hasn't had a cig since and he smoked 2 pouches of tobacco a day.  X onward towards that new car.lolx

[Kenneth131]

I think what the study was saying is that ecigs satisfy the nicotine craving we get but does not reduce your dependancy on the drug although again I would like to see larger studies on this since a lot of members on here have reduced nic levels however that's for a later study I guess

Glad you made the switch and glad your enjoying it. Over time you will feel better as well 

[Thurlow99]

Fantasic Ty,
i am obessed by these such reports and indeed by any medical writtings on addiction, alan sums up nicotine addiction best.. read his book "easy way" and theres nothing you wont know about Nic Ad.

[richjhewitt]

Only just read this as have been MIA for the last few months.

Makes for very interesting reading, will be showing this to a few people.

Thanks very much for sharing Astrecks!

Rich

[Elisia10]

Wow! This article is extremely interesting! They have done a good job

[Valroc]

I work at the University of Bradford in cognition and cognitive enhancers. 

I have worked with nicotine on a professional level many times to see its effects and we have shown the clear improvements in cognition that is shown when under the influence of nicotine .

It is also good to note its appetite suppressive ability too .

Nicotine by itself is similar to caffeine.  Its just the stigma that analogues has given it that causes people to think that it is bad.  It is not only the nicotine that causes the addiction.  The other few thousand chemicals in analogues also contributes to the addictive nature of smoking.

Gotta love vaping .

[MONEYMAN]

Celebrating ONE YEAR AND ONE WEEK without an anolog...............thanks again TW

[canniscam]

Congrats MONEYMAN!

Vape On!

-Casey

[MONEYMAN]

37 YEAR..............2 packs a day and 2 heart attacks gone forever

[chops]

Fabulous news moneyman, congratulations . I wish that electronic cigarettes had been around many years ago... Hon Lik and Ruyan had no idea what an impact their first marketing of the electronic cigarette would have on life and health

[mstclair87]

I work at the University of Bradford in cognition and cognitive enhancers. 

...

Nicotine by itself is similar to caffeine.

...

Gotta love vaping .

Valroc, when you say "similar", do you know the ratio of the effects of these two substances, e.g. how many vapes at a given strength equate to a double espresso?

[Kenneth131]

I think he means the effects of nicotine on the body as a stimulant are no more harmful than that of caffeine I don't think its directly comparable

[canniscam]

Yeah the most definitely Ken..   As both chemicals are stimulants they effects can be similar but not identical.

Casey

[mstclair87]

Yeah the most definitely Ken..   As both chemicals are stimulants they effects can be similar but not identical.

Casey

One similarity is that both are poisons. See http://www.actionbioscience.org/environment/trautmann.html for what I found an interesting discussion of this topic. I suppose I could ask how much nicotine would kill you compared with how much caffeine, though I'm not actually trying to kill myself - the opposite, in fact! Therefore nicotine and caffeine must be comparable in respect of toxicity, though I'm also interested in the effects on the metabolism - the similarity that Valroc mentions. I suppose if it was true that x mg of caffeine has the same toxicity at y mg of nicotine then I'd have partly answered my question: the answer would be that milligram for milligram caffeine is y/x times as poisonous as nicotine. I'll try and find this out and post the answer back here. Next point, which must be relatively easy to ascertain, is how much caffeine is there in a cup of coffee and how much nicotine in a single vape. Then we could do a direct comparison, perhaps qualified by knowledge about how much of the nicotine one vapes actually goes into one's blood, a question that still seems in some doubt.

[Astrecks]

A quick google search reveals the Lethal Dose of nicotine or caffeine in rats as:

Caffeine 192mg/kg
Nicotine 50mg/kg

I also found a "How much caffeine would kill me" calculator which gave the following results for a 12stone (154 pounds) person.

337 cans of Classic coke
243 cups of tea
168 cups of instant coffee
148 cups of espresso coffee
143 cans of Red Bull

[mstclair87]

A quick google search reveals the Lethal Dose of nicotine or caffeine in rats as:

Caffeine 192mg/kg
Nicotine 50mg/kg

I also found a "How much caffeine would kill me" calculator which gave the following results for a 12stone (154 pounds) person.

...
148 cups of espresso coffee
...

Thanks for that. Let's say that a 12-stone (76kg) person would find 14.6g (76 x 0.192) of caffeine fatal. That's 148 cups of espresso, at about 100mg per cup.

It looks like nicotine is nearly 4 times as poisonous as caffeine weightwise.

I read that one absorbs about 1mg of nicotine from one analogue cigarette. (I haven't any idea how much nicotine one gets from a vape, so my calculation will need to be reworked once we have some idea of that). For the amount of nicotine consumed to have the same toxicity as one cup of espresso, we need 1/148th of of the fatal dose. A fatal dose of nicotine for a 12-stone (76kg) person is 3.8g (76 x 0.05), so the caffeine in one cup of espresso has an equivalent toxicity to about 25mg (3800/148) of nicotine, or 25 analogue cigarettes.

I'm not quite sure where that gets us. It may not be reasonable to assume that there is a direct correlation between the effects of these substances and the amounts consumed, though I'm assuming that here. What it looks like is that, whilst the effects of nicotine and caffeine may be similar in some respects, one's got to do quite a lot of inhaling, like 25 times as much smoking as one might normally do per cup of coffee, in order to obtain the same level level of effect from both substances (at least in terms of toxicity).

Matthew

[Astrecks]

I'm glad you worked that out, lol

For what it is worth, I have been vaping for just over 3 years, initially at 36mg for the first 18months, and now 6mg....I'm still here 

[mstclair87]

If I vape 3ml of eliquid per day at 18ml/mg nicotine strength, then I'm in theory ingesting 54mg of nicotine, the same amount of nicotine as I'd get from 54 analogues. In toxicological terms, that's the same level of lethality as in about two cups of coffee. In other words, not very poisonous.

I am suspicious of my own assumptions here, however. Just because a certain dose of something is fatal doesn't mean that a much smaller dose isn't going to have a harmful effect, particularly if it's repeated regularly. For instance, even though I've calculated that I'd need to smoke 25 analogues to poison me to the same extent as one cup of coffee, I only needed one analogue (and now just a few vapes) with a cup of coffee to feel good. More research needed, I think!

Matthew

[terrier]

Fred,Ken, Valroc

I have reduced my nic down to ZERO,  I don't feel as if my memory is any different, if I did question is would I go back to nic and at what strength??

terrier

[hypnofolk]

If I vape 3ml of eliquid per day at 18ml/mg nicotine strength, then I'm in theory ingesting 54mg of nicotine, the same amount of nicotine as I'd get from 54 analogues. In toxicological terms, that's the same level of lethality as in about two cups of coffee. In other words, not very poisonous.

I am suspicious of my own assumptions here, however. Just because a certain dose of something is fatal doesn't mean that a much smaller dose isn't going to have a harmful effect, particularly if it's repeated regularly. For instance, even though I've calculated that I'd need to smoke 25 analogues to poison me to the same extent as one cup of coffee, I only needed one analogue (and now just a few vapes) with a cup of coffee to feel good. More research needed, I think!

Matthew

I worked in the medical trials field for a couple of years ( I am not a doctor, I am a programmer ), and what I notice about this topic is that nobody is considering
the time the body needs to get rid of a certain amount of toxic substance. In case of nicotine/caffeine I think it would be to consider the hours/mg ratio. I know for nicotine is quiet quick.

[mstclair87]

I think the measure here is the half-life - the time it takes for the amount of a substance in the system to reduce by half. If I remember, Carr, in The Easy Way To Give Up Smoking, indicates that nicotine's half-life is half an hour, though I've seen it elsewhere stated as two hours (http://en.wikipedia.org/wiki/Nicotine). And for caffeine, it's five hours (http://en.wikipedia.org/wiki/Caffeine), i.e. caffeine stays in the system for at least two and a half times longer. Or I suppose, put another way, if you take a gap of five hours between cups of coffee, you only need to take a gap of two hours between smokes for a dose of a given qualitative effect.

[Timinwales]

For the record, since starting Vaping because I ran out of baccy, was feeling particularly knackered and couldn't be bothered walking up the shop, so I borrowed the other halfs Ego C ... There's a wee bit more to it to be fair but that's the crux. I haven't had a stinky or felt the urge to, I was smoking about 12 to 18 rollies a day so although not much by many standards enough and for long enough that it was a habit rather than anything else..... I did and still do to a point really miss rolling them though, now I clean threads, top up tanks and such instead.

I'm aware this isn't the way of things for everyone, and I didn't plan on stopping smoking, it just happened that way no complaints I still get my nicotine hit, it tastes nicer (I'm amazed how much I notice the smell of fag smoke) and smells better, I'm assuming it's considerably more socially acceptable(not on the whole something I'd be over bothered about) because the PV generates interest rather than frowns or tuts, but over all I do feel better for it now, placebo effect perhaps?